Isopentenyl pyrophosphate-reactive Vgamma9Vdelta 2 T helper 1-like cells are the major gammadelta T cell subset recovered from lesions of patients with genital herpes.

@article{Verjans2004IsopentenylPV,
  title={Isopentenyl pyrophosphate-reactive Vgamma9Vdelta 2 T helper 1-like cells are the major gammadelta T cell subset recovered from lesions of patients with genital herpes.},
  author={Georges M G M Verjans and Rosalien Roest and Alex van der Kooi and Grietje van Dijk and Wim I van der Meijden and Albert 'D M E Osterhaus},
  journal={The Journal of infectious diseases},
  year={2004},
  volume={190 3},
  pages={
          489-93
        }
}
Herpes simplex virus (HSV)-specific T cells are essential to control and resolve genital herpes (GH). To investigate the potential involvement of gamma delta T cells in GH, T cells were recovered and expanded, by mitogenic stimulation, to T cell lines from the genital lesions of 17 patients with GH and 5 control subjects who had other diseases. Relatively high numbers of gamma delta T cells--predominantly, V gamma 9V delta 2 T cells--were detected only in the T cell lines of the patients with… CONTINUE READING