Isoniazid in the treatment of chronic lupus erythematosus.

  title={Isoniazid in the treatment of chronic lupus erythematosus.},
  author={B. Appel and G. R. Baler and E. Dougherty},
  journal={A.M.A. archives of dermatology and syphilology},
  volume={68 4},
  • B. Appel, G. R. Baler, E. Dougherty
  • Published 1953
  • Medicine
  • A.M.A. archives of dermatology and syphilology
  • CHRONIC lupus erythematosus is notoriously resistant to treatment. Until 1951, bismuth, gold, and arsenic were the principal systemic agents; second choices were suramin sodium (Naphuride), 1 quinine, crude liver extract, and vitamin E; third choice was local destruction, usually with carbon dioxide. In 1951, quinacrine (Mepacrine, Atabrine) was reported by Page 2 to have produced excellent results, and personal reports to us by several dermatologists indicate an increasing confirmation of good… CONTINUE READING
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