Isoniazid concentrations in hair and plasma area-under-the-curve exposure among children with tuberculosis

Abstract

We measured hair and plasma concentrations of isoniazid among sixteen children with tuberculosis who underwent personal or video-assisted directly observed therapy and thus had 100% adherence. This study therefore defined typical isoniazid exposure parameters after two months of treatment among fully-adherent patients in both hair and plasma (plasma area… (More)
DOI: 10.1371/journal.pone.0189101

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