Isomeric complexity of glycosylation documented by MSn.

  title={Isomeric complexity of glycosylation documented by MSn.},
  author={David J. Ashline and Hailong Zhang and Vernon N. Reinhold},
  journal={Analytical and bioanalytical chemistry},
  volume={409 2},
Re-analysis of two breast cancer cell lines, MCF-7 and MDA-MB-231, has shown multiple isomeric structures exposed by sequential mass spectrometry, MS n . Several released glycan compositions were re-evaluated, which indicated variations in polylactosamine and fucosylation structures. Probable isomer numbers, when considering both stereo and structural… CONTINUE READING