Isomer-specific effects of conjugated linoleic acid on mineralized bone nodule formation from human osteoblast-like cells.

@article{Platt2007IsomerspecificEO,
  title={Isomer-specific effects of conjugated linoleic acid on mineralized bone nodule formation from human osteoblast-like cells.},
  author={Ilana D Platt and Leticia Gomez Rao and Ahmed El-Sohemy},
  journal={Experimental biology and medicine},
  year={2007},
  volume={232 2},
  pages={246-52}
}
Mixed isomers of conjugated linoleic acid (CLA) have been shown to have variable effects on bone formation and resorption in animals. The variable effects of CLA on bone physiology may be due to the different isomers present in common commercial preparations of CLA, and the effects of the predominant individual isomers (9cis,11trans and 10trans,12cis CLA) are not clear. The objective of this study was to determine the effects of individual and mixed isomers of CLA on mineralized bone nodule… CONTINUE READING

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