Isolation versus grouped housing in rats: differential effects of low doses of heroin in the place preference paradigm.

@article{Schenk1983IsolationVG,
  title={Isolation versus grouped housing in rats: differential effects of low doses of heroin in the place preference paradigm.},
  author={Susan Schenk and Thomas Hunt and Lois M. Colle and Zalman Amit},
  journal={Life sciences},
  year={1983},
  volume={32 10},
  pages={
          1129-34
        }
}
Male Long Evans rats were reared from weaning (21-23 days) either in isolation or in groups of four for 40 days. Animals were then individually introduced to a testing apparatus consisting of two distinct chambers. A modified place preference paradigm was used consisting of 3 phases: (1) An habituation phase (4 days) during which rats were allowed free access to the entire test apparatus for 15 min. periods daily; (2) A conditioning phase (4 days) during which rats were confined to their non… CONTINUE READING

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