Isolation of thrombospondin released from thrombin-stimulated human platelets by fast protein liquid chromatography on an anion-exchange Mono-Q column.

Abstract

Thrombospondin, a glycoprotein found in human platelet alpha granules, is thought to play a major role in platelet haemostatic functions. A rapid method to isolate thrombospondin for functional and structural studies was developed. Freshly prepared supernatants from thrombin-stimulated platelets were separated on an anion-exchange Mono-Q column on a fast… (More)

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@article{Clzardin1984IsolationOT, title={Isolation of thrombospondin released from thrombin-stimulated human platelets by fast protein liquid chromatography on an anion-exchange Mono-Q column.}, author={Philippe Cl{\'e}zardin and James McGregor and Michel Manach and F. Robert and Marc Dechavanne and Ken J Clemetson}, journal={Journal of chromatography}, year={1984}, volume={296}, pages={249-56} }