Isolation of the uterotonic principle from Leonurus artemisia, the Chinese motherwort.

@article{Kong1976IsolationOT,
  title={Isolation of the uterotonic principle from Leonurus artemisia, the Chinese motherwort.},
  author={Young Hee Kong and Henry Wai-chung Yeung and Yiu Man Cheung and J. C. Hwang and Yew Weng Chan and Y P Law and Kian Hong Ng and C. H. Yeung},
  journal={The American journal of Chinese medicine},
  year={1976},
  volume={4 4},
  pages={373-82}
}
A search in ancient Chinese medicinal literature and modern phytochemical references indicates that the therapeutic value of Leonurus artemisia (I-mu ts'ao, the Chinese motherwort) might reside in a uterotonic principle present in leaves. Leonurine (4-guanidino-n-butyl syringate) was isolated from fresh and dry leaves of Leonurus artemisia. The uterotonic effect of leonurine was demonstrated in rat uterus in vitro. Results from this study suggest that functional phytochemistry based on… CONTINUE READING

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