Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells

@article{Hattori1996IsolationOT,
  title={Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells},
  author={Noboru Hattori and Hiroshi Kawamoto and Yoshimoto Katsura},
  journal={The Journal of Experimental Medicine},
  year={1996},
  volume={184},
  pages={1901 - 1908}
}
Thymus cells of murine fetuses at day 12 of gestation are exclusively of the CD3-CD4-CD8-CD44+CD25- phenotype, which is known as a hallmark of the most immature subset of thymus cells. In the present study, we show that day 12 fetal thymus (FT) cells express Fc gamma RII/ III (FcR) at a broad range of levels on their surface. The FcR+ FT cells seem to represent T lineage cells, because a large majority of them express the T lineage specific transcription factors TCF-1 and GATA-3 as well as CD3… CONTINUE READING
23 Citations
3 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

References

Publications referenced by this paper.
Showing 1-3 of 3 references

Lymphocyte development from stern cells

  • K. Ikuta, N. Uchida, J. Friedman, I.L
  • Welssman
  • 1992

Similar Papers

Loading similar papers…