Isolation of the intercellular glycoproteins of desmosomes


To characterize the desmosome components that mediate intercellular adhesion and cytoskeletal-plasma membrane attachment, we prepared whole desmosomes and isolated desmosomal intercellular regions (desmosomal "cores") from the living cell layers of bovine muzzle epidermis. The tissue was disrupted in a nonionic detergent at low pH, sonicated, and the… (More)


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@article{Gorbsky1981IsolationOT, title={Isolation of the intercellular glycoproteins of desmosomes}, author={Gary J Gorbsky and Michael S Steinberg}, journal={The Journal of Cell Biology}, year={1981}, volume={90}, pages={243 - 248} }