Isolation of the chicken NF-kappa B p65 subunit-encoding cDNA and characterization of its products.

@article{Ikeda1993IsolationOT,
  title={Isolation of the chicken NF-kappa B p65 subunit-encoding cDNA and characterization of its products.},
  author={Takako Ikeda and Kazuhito Honjo and Yukinori Hirota and Tomomi Onodera},
  journal={Gene},
  year={1993},
  volume={133 2},
  pages={237-42}
}
NF-kappa B is a heterodimeric transcription factor consisting of subunits of 50 kDa (p50) and 65 kDa (p65). cDNA clones encoding the chicken NF-kappa B p65 subunit were isolated. Sequence analysis showed that chicken p65 is approximately 55% identical to the mouse and human p65 proteins, and contains the Rel homology domain (RHD) in its N-terminal 286 amino acids (aa) and the putative transactivation domain in its C-terminal region. The RHD is particularly highly conserved between the chicken… CONTINUE READING
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