Isolation of steroidal glycosides from the Caribbean sponge Pandaros acanthifolium.

@article{Berru2012IsolationOS,
  title={Isolation of steroidal glycosides from the Caribbean sponge Pandaros acanthifolium.},
  author={F. Berru{\'e} and M. W. McCulloch and P. Boland and S. Hart and M. K. Harper and James Johnston and R. Kerr},
  journal={Journal of natural products},
  year={2012},
  volume={75 12},
  pages={
          2094-100
        }
}
Four new steroidal glycosides, acanthifoliosides G-J (1-4), were isolated as minor constituents from the Caribbean marine sponge Pandaros acanthifolium. These metabolites are characterized by a highly oxygenated D ring and the presence of a disaccharide rhamnose-glucose residue and a rhamnose at positions C-3 and C-15, respectively. Their structures were established on the basis of extensive interpretation of 1D and 2D NMR data and HRESIMS analyses. The absolute configurations of the glucose… Expand
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Six new steroidal saponins, pandarosides K-M and their methyl esters (4-6), were isolated as minor components, after a careful chemical reinvestigation of the Caribbean sponge Pandaros acanthifolium, and showed moderate to weak activity against four parasitic protozoa. Expand
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