Isolation of sphingoid bases of sea cucumber cerebrosides and their cytotoxicity against human colon cancer cells.

@article{Sugawara2006IsolationOS,
  title={Isolation of sphingoid bases of sea cucumber cerebrosides and their cytotoxicity against human colon cancer cells.},
  author={Tatsuya Sugawara and Nobuhiro Zaima and Akiyo Yamamoto and Shota Sakai and Ryoko Noguchi and Takashi Hirata},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2006},
  volume={70 12},
  pages={2906-12}
}
Sea cucumber is a health-beneficial food, and contains a variety of physiologically active substances including glycosphingolipids. We show here the sphingoid base composition of cerebrosides prepared from sea cucumber and the cytotoxicity against human colon cancer cell lines. The composition of sphingoid bases prepared from sea cucumber was different from that of mammals, and the major constituents estimated from mass spectra had a branched C17-19 alkyl chain with 1-3 double bonds. The… CONTINUE READING
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