Isolation of plasma membrane–associated membranes from rat liver

  title={Isolation of plasma membrane–associated membranes from rat liver},
  author={Jan M. Suski and Magdalena Lebiedzińska and Aleksandra Wojtala and Jerzy Duszyński and Carlotta Giorgi and Paolo Pinton and Mariusz Roman Wieckowski},
  journal={Nature Protocols},
Dynamic interplay between intracellular organelles requires a particular functional apposition of membrane structures. The organelles involved come into close contact, but do not fuse, thereby giving rise to notable microdomains; these microdomains allow rapid communication between the organelles. Plasma membrane–associated membranes (PAMs), which are microdomains of the plasma membrane (PM) interacting with the endoplasmic reticulum (ER) and mitochondria, are dynamic structures that mediate… CONTINUE READING

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