Isolation of oligodendrocyte-like cells from human umbilical cord blood.

  title={Isolation of oligodendrocyte-like cells from human umbilical cord blood.},
  author={Elizabeth T. Tracy and Jennifer Hall Aldrink and Jennifer Panosian and Donald S Beam and Jnanesh Thacker and Melissa Reese and Joanne Kurtzberg},
  volume={10 5},
BACKGROUND As human umbilical cord blood (UCB) is known to be a rich source of progenitor cells, the prospect of isolating a subset of these cells that could differentiate into cells of non-hematopoietic lineages suggests a therapeutic use for patients with inherited lysosomal and peroxisomal storage diseases currently treated with UCB transplantation. METHODS Oligodendrocyte-like cells were isolated from UCB by density-gradient centrifugation and expanded using selective media. We then… CONTINUE READING


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