Isolation of mycobacteria in patients with pulmonary alveolar proteinosis.

  title={Isolation of mycobacteria in patients with pulmonary alveolar proteinosis.},
  author={L A Witty and Victor F. Tapson and Claude A. Piantadosi},
  volume={73 2},
Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by accumulation of proteinaceous material in the alveoli of affected individuals. Pulmonary infections appear to develop with increased frequency in these patients. The increased rate of infection has been attributed to immunologic aberrations, such as impaired alveolar macrophage function, particularly when uncommon pathogens are involved. Among those pathogens, Nocardia asteroides and Mycobacterium tuberculosis have… CONTINUE READING
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