Isolation of individual cellular components from lung tissues of patients with lymphangioleiomyomatosis.

Abstract

Lymphangioleiomyomatosis (LAM) is a rare neoplastic disease entailing cystic destruction of the lungs and progressive respiratory failure. LAM lungs are histologically characterized by the proliferation of smooth muscle-like cells (LAM cells) and an abundance of lymphatic vessels. To elucidate the pathophysiological processes of LAM, cell-type-specific… (More)
DOI: 10.1152/ajplung.00365.2015

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