Isolation of factor Xa from chick embryo as the amniotic endoprotease responsible for paramyxovirus activation
@article{Gotoh1992IsolationOF, title={Isolation of factor Xa from chick embryo as the amniotic endoprotease responsible for paramyxovirus activation}, author={Bin Gotoh and Fumi Yamauchi and T. Ogasawara and Yoshiyuki Nagai}, journal={FEBS Letters}, year={1992}, volume={296} }
36 Citations
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An endoprotease from chick embryo is isolated, that activates para‐ and orthomyxovirus fusion glycoproteins by cleaving their precursor proteins at a specific, single arginine site and was found to be highly homologous, if not identical, to the blood clotting factor X(FX), a member of the prothrombin family.
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The pathogenic strain Italien and the apathogenic strain Ulster of Newcastle disease virus have been compared with respect to organ tropism and spread of infection in 11-day-old chick embryos. After…
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