Isolation of dinophysistoxin-2 and the high-performance liquid chromatographic analysis of diarrhetic shellfish toxins using derivatisation with 1-bromoacetylpyrene.

@article{Kelly1996IsolationOD,
  title={Isolation of dinophysistoxin-2 and the high-performance liquid chromatographic analysis of diarrhetic shellfish toxins using derivatisation with 1-bromoacetylpyrene.},
  author={S. S. Kelly and Andrea G. Bishop and E. P. Carmody and K. James},
  journal={Journal of chromatography. A},
  year={1996},
  volume={749 1-2},
  pages={
          33-40
        }
}
  • S. S. Kelly, Andrea G. Bishop, +1 author K. James
  • Published 1996
  • Chemistry, Medicine
  • Journal of chromatography. A
    • The rare diarrhetic shellfish toxin, dinophysistoxin-2 (DTX-2), was isolated from the digestive glands of mussels (Mytilus edulis). This was achieved by chromatography on silica and Sephadex LH-20 followed by reversed-phase solid phase extraction and semi-preparative high-performance liquid chromatography (HPLC) with an Ultremex C18 column. Using 1-bromoacetylpyrene (BAP), as a precolumn derivatisation reagent, the diarrhetic shellfish toxins, okadaic acid (OA), dinophysistoxin-1 (DTX-1) and… CONTINUE READING
    View on PubMed
    doi.org
    23 Citations
    Background Citations
    2
    Methods Citations
    1
    23 Citations
    Citation Type

    Citation Type

    Identification of a new diarrhoetic toxin in shellfish using liquid chromatography with fluorimetric and mass spectrometric detection.
    • 24
    Improvement on sample clean-up for high-performance liquid chromatographic-fluorimetric determination of diarrhetic shellfish toxins using 1-bromoacetylpyrene.
    • 12
    Liquid chromatographic methods for the isolation and identification of new pectenotoxin-2 analogues from marine phytoplankton and shellfish.
    • 64
    Determination of okadaic acid, dinophysistoxin-1 and related esters in Greek mussels using HPLC with fluorometric detection, LC-MS/MS and mouse bioassay.
    • 50
    Use of immunoaffinity columns for clean-up of diarrhetic toxins (okadaic acid and dinophysistoxins) extracts from shellfish prior to their analysis by HPLC/fluorimetry.
    • 17
    Detection of okadaic acid and related esters in mussels during diarrhetic shellfish poisoning (DSP) episodes in Greece using the mouse bioassay, the PP2A inhibition assay and HPLC with fluorimetric detection.
    • 48
    Confirmation of okadaic acid, dinophysistoxin-1 and dinophysistoxin-2 in shellfish as their anthrylmethyl derivatives using UV radiation.
    • 2
    Efficient isolation of the rare diarrhoeic shellfish toxin, dinophysistoxin-2, from marine phytoplankton.
    • 38
    Occurrence of diarrhetic shellfish poisoning (DSP) toxins in clams (Ruditapes decussatus) from Tunis north lagoon
    • 18
    Comparison of solid-phase extraction methods for the determination of azaspiracids in shellfish by liquid chromatography-electrospray mass spectrometry.
    • 18

    References

    SHOWING 1-8 OF 8 REFERENCES
    Dinophysistoxin-2: the predominant diarrhoetic shellfish toxin in Ireland.
    • 71
    Diarrhetic shellfish poisoning : evaluation of enzyme-linked immunosorbent assay methods for determination of dinophysistoxin-2
    • 20
    • PDF
    Phycotoxins in seafood--toxicological and chromatographic aspects.
    • B. Luckas
    • Chemistry, Medicine
    • Journal of chromatography
    • 1992
    • 53
    N-(9-acridinyl)-bromoacetamide--a powerful reagent for phase-transfer-catalyzed fluorescence labeling of carboxylic acids for liquid chromatography.
    • 28
    Isolation of a new diarrhetic shellfish poison from Irish mussels
    • 93
    Okadaic acid: a new probe for the study of cellular regulation.
    • 1,247
    Harmful Marine Algal Blooms
    • 503
    TOXIC PHYTOPLANKTON BLOOMS IN THE SEA
    • 982