Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis).

@article{Leo2002IsolationOD,
  title={Isolation of dengue 2 virus from a patient with central nervous system involvement (transverse myelitis).},
  author={Raimundo N Q Le{\~a}o and Teichi Oikawa and Elizabeth Salb{\'e} T Rosa and Jos{\'e} Takao Yamaki and Sueli Guerreiro Rodrigues and Helena Baldez Vasconcelos and Maria Rui Sousa and Jaime K Tsukimata and Raimunda do Socorro da Silva Azevedo and Pedro Fernando da Costa Vasconcelos},
  journal={Revista da Sociedade Brasileira de Medicina Tropical},
  year={2002},
  volume={35 4},
  pages={401-4}
}
A dengue fever case is described in a 58-year-old male patient with febrile illness and thrombocytopenia complicated by neurological involvement characterized by transverse myelitis followed by weakness of both legs and flaccid paralysis. Muscle strength was much diminished and bilateral areflexia was observed. Dengue 2 (DEN-2) virus was isolated and the patient sero-converted by hemagglutination-inhibition and IgM-ELISA tests. The RT-PCR test was positive to DEN-2 in acute phase serum and… CONTINUE READING
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