Isolation of circulating angiogenic cells.

  title={Isolation of circulating angiogenic cells.},
  author={Erin E. Vaughan and Timothy O'Brien},
  journal={Methods in molecular biology},
Endothelial progenitor cells (EPCs) were first identified by Ashara et al. in 1997 (Asahara et al. Science 275:964-967, 1997) and were thought to contribute to angiogenesis and vasculogenesis. Since their discovery, circulating levels of EPCs were found to serve as biomarkers as low levels correlate with increased cardiovascular events and death from cardiovascular causes (Werner et al. N Engl J Med 353:999-1007, 2005; Fadini et al. J Am Coll Cardiol 45:1449-1457, 2005; Hill et al. N Engl J Med… CONTINUE READING

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