Isolation of cDNAs encoding immunogenic regions of gp330, the autoantigen involved in Heymann nephritis.

Abstract

Active Heymann nephritis is an organ-specific autoimmune disease of the rat kidney, characterized by the formation of immune complexes located subepithelially in the glomerulus. The T cell-mediated humoral immune response is directed to gp330, a large renal epithelial glycoprotein which is expressed both in the proximal tubule and on glomerular podocytes… (More)

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@article{Luca1996IsolationOC, title={Isolation of cDNAs encoding immunogenic regions of gp330, the autoantigen involved in Heymann nephritis.}, author={Mariken E Luca and Bernard de Geus and Djillali Sahali and Jan Anthonie Bruijn and Pierre J. Verroust and Emile de Heer}, journal={Clinical and experimental immunology}, year={1996}, volume={104 2}, pages={312-7} }