Isolation of bovine coronavirus from feces and nasal swabs of calves with diarrhea.

  title={Isolation of bovine coronavirus from feces and nasal swabs of calves with diarrhea.},
  author={Hiroshi Tsunemitsu and H Yonemichi and Tuneo Hirai and Tadaaki Kudo and Sadao Onoe and Kazuhiko Mori and Manabu Shimizu},
  journal={The Journal of veterinary medical science},
  volume={53 3},
Fecal and nasal samples were collected from 180 calves with diarrhea and 36 clinically normal co-habitants, and tested for virus using HRT-18 cell cultures derived from human rectal adenocarcinoma. A cytopathic virus was isolated from 5 fecal and 56 nasal samples obtained from diarrheic calves. All calves in which the virus was isolated from diarrheic feces were positive for virus isolation from nasal swabs. The virus was also isolated from the nasal swabs of 10 clinically normal calves that… CONTINUE READING


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