Isolation of avirulent clones of Candida albicans with reduced ability to recognize the CR2 ligand C3d.

@article{Franzke1993IsolationOA,
  title={Isolation of avirulent clones of Candida albicans with reduced ability to recognize the CR2 ligand C3d.},
  author={Stefanie A. Franzke and Richard A. Calderone and K. -H. Schaller},
  journal={Infection and immunity},
  year={1993},
  volume={61 6},
  pages={2662-9}
}
Four clones of the yeast Candida albicans, isolated on the basis of their tolerance to clotrimazole, were compared with their parental strains in terms of growth, morphology, virulence, and cell surface complement receptor activity. In a newly described synthetic medium, these clones, designated C1, C2, N, and P, produced germ tubes or pseudohyphae, but no true hyphae, in a pattern which was specific for each strain. The growth of each clone at 37 degrees C, under conditions which favor the… CONTINUE READING