Isolation of an antileishmanial and antitrypanosomal flavanone from the leaves of Baccharis retusa DC. (Asteraceae)

@article{Grecco2010IsolationOA,
  title={Isolation of an antileishmanial and antitrypanosomal flavanone from the leaves of Baccharis retusa DC. (Asteraceae)},
  author={Simone dos Santos Grecco and Juliana Quero Reim{\~a}o and Andre Gustavo Tempone and Patr{\'i}cia Sartorelli and Paulete Romoff and Marcelo J. P. Ferreira and Oriana A. F{\'a}vero and Jo{\~a}o Henrique Guilardi Lago},
  journal={Parasitology Research},
  year={2010},
  volume={106},
  pages={1245-1248}
}
In the course of selection of new bioactive compounds from Brazilian flora, the crude MeOH extract from the leaves of Baccharis retusa DC. (Asteraceae) showed potential against Leishmania sp. and Trypanosoma cruzi. Chromatographic fractionation of the dichloromethane phase from MeOH extract yielded great amounts of the bioactive derivative, which was… CONTINUE READING