Isolation of an antigen fraction from Setaria cervi adults having potential for immunodiagnosis of human filariasis.

@article{Kaushal2009IsolationOA,
  title={Isolation of an antigen fraction from Setaria cervi adults having potential for immunodiagnosis of human filariasis.},
  author={Nuzhat A. Kaushal and Neelu Srivastava and Huma Mustafa and Ashish Tandon and Shravan Kumar Singh and Deep C Kaushal},
  journal={Immunological investigations},
  year={2009},
  volume={38 8},
  pages={749-61}
}
Crude antigenic preparations from heterologous filarial parasites gave false positive results because of complex nature of these antigens and their cross-reactivity with other helminth parasites. In the present study, efforts have been made to isolate and characterize the antigens from Setaria cervi important for diagnostic purposes. The fractionation of S. cervi somatic antigenic preparation on Sephacryl S-200 resulted in separation of three major antigenic peak fractions. Crossed… CONTINUE READING
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