Isolation of an acid fraction from a fish protein hydrolysate with a calcitonin-gene-related-peptide-like biological activity.

@article{FouchereauPron1999IsolationOA,
  title={Isolation of an acid fraction from a fish protein hydrolysate with a calcitonin-gene-related-peptide-like biological activity.},
  author={Martine Fouchereau-P{\'e}ron and L Duvail and Christian Michel and Asbjoern Gildberg and Irineu Batista and Yves Le Gal},
  journal={Biotechnology and applied biochemistry},
  year={1999},
  volume={29 ( Pt 1)},
  pages={87-92}
}
The possibility of obtaining calcitonin and/or calcitonin-gene-related peptide (CGRP) immunorelated molecules from partly digested proteins was investigated with fish and shrimp hydrolysates. These two peptides were quantified by both radioimmunoassay and radioreceptor assay; the positive extracts were partly purified. Different hydrolysates were analysed: cod head, stomach and viscera hydrolysates, a shrimp hydrolysate and two sardine hydrolysates. Although each cod extract interacted in the… CONTINUE READING