Isolation of an N-acetyl-D-glucosamine specific lectin from the rhizomes of Arundo donax with antiproliferative activity.

@article{Kaur2005IsolationOA,
  title={Isolation of an N-acetyl-D-glucosamine specific lectin from the rhizomes of Arundo donax with antiproliferative activity.},
  author={Amandeep Kaur and Jatinder Singh and Sukhdev Singh Kamboj and Ashok K Sexana and Renu Moti Pandita and M Shamnugavel},
  journal={Phytochemistry},
  year={2005},
  volume={66 16},
  pages={1933-40}
}
A lectin with antiproliferative activity towards human cancer cell lines and mitogenic towards human peripheral blood mononuclear cells was purified from the rhizomes of Arundo donax (Linn.) by affinity chromatography on N-acetyl-d-glucosamine linked to epoxy-activated sepharose-6B. The pure preparation apparently yielded a single band of approximately 15 kDa on SDS-PAGE, pH 8.3, under both reducing and non-reducing conditions. The molecular mass of native lectin was 32 kDa as determined by gel… CONTINUE READING
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