Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain.

@article{Mirold1999IsolationOA,
  title={Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain.},
  author={Susanne Mirold and Wolfgang Rabsch and Manfred Rohde and Silke Stender and Helmut Tsch{\"a}pe and Holger Ruessmann and Elena Igwe and Wolf Dietrich Hardt},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 17},
  pages={
          9845-50
        }
}
Salmonella typhimurium employs the specialized type III secretion system encoded in pathogenicity island 1 (SPI1) to translocate effector proteins into host cells and to modulate host cell signal transduction. The SPI1 type III system and the effector proteins are conserved among all salmonellae and are thought to be acquired by horizontal gene transfer. The genetic mechanisms mediating this horizontal transfer are unknown. Here, we describe that SopE, a SPI1-dependent translocated effector… CONTINUE READING

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