Isolation of a sulfate ester of hyaluronic acid from heart valves.


The most characteristic componems of the intercellular matrix, or ground substance, of connective tissue are the highly polymerized acid mucopolysaccharides. Meyer and Rapport (1) distinguish five such acid mucopolysaccharides isolated from ground substance: three chondroitin sulfates (A, B, and C), hyaluronic acid, and hyaluronosulfate. These polymers have… (More)


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