Isolation of a novel visual-system-specific arrestin: an in vivo substrate for light-dependent phosphorylation.

@article{Levine1990IsolationOA,
  title={Isolation of a novel visual-system-specific arrestin: an in vivo substrate for light-dependent phosphorylation.},
  author={Herbert Levine and Dean Smith and Mike Whitney and Denise M. Malicki and Patrick J. Dolph and Graham Smith and William Burkhart and Charles S. Zuker},
  journal={Mechanisms of development},
  year={1990},
  volume={33 1},
  pages={19-25}
}
Absorption of a photon of light by rhodopsin triggers mechanisms responsible for excitation as well as regulation of the phototransduction cascade. Arrestins are a family of proteins that appear to be responsible for terminating the active state of G-protein-coupled receptors. One of the major substrates of light-dependent phosphorylation in the visual cascade of Drosophila was purified and partially sequenced. The complete primary structure of the protein was determined by isolating the… CONTINUE READING
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