Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia.

  title={Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia.},
  author={A. Zaki and S. van Boheemen and T. Bestebroer and A. Osterhaus and R. Fouchier},
  journal={The New England journal of medicine},
  volume={367 19},
  • A. Zaki, S. van Boheemen, +2 authors R. Fouchier
  • Published 2012
  • Medicine
  • The New England journal of medicine
  • A previously unknown coronavirus was isolated from the sputum of a 60-year-old man who presented with acute pneumonia and subsequent renal failure with a fatal outcome in Saudi Arabia. The virus (called HCoV-EMC) replicated readily in cell culture, producing cytopathic effects of rounding, detachment, and syncytium formation. The virus represents a novel betacoronavirus species. The closest known relatives are bat coronaviruses HKU4 and HKU5. Here, the clinical data, virus isolation, and… CONTINUE READING
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