Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia.
@article{Zaki2012IsolationOA, title={Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia.}, author={A. Zaki and S. van Boheemen and T. Bestebroer and A. Osterhaus and R. Fouchier}, journal={The New England journal of medicine}, year={2012}, volume={367 19}, pages={ 1814-20 } }
A previously unknown coronavirus was isolated from the sputum of a 60-year-old man who presented with acute pneumonia and subsequent renal failure with a fatal outcome in Saudi Arabia. The virus (called HCoV-EMC) replicated readily in cell culture, producing cytopathic effects of rounding, detachment, and syncytium formation. The virus represents a novel betacoronavirus species. The closest known relatives are bat coronaviruses HKU4 and HKU5. Here, the clinical data, virus isolation, and… CONTINUE READING
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References
SHOWING 1-10 OF 29 REFERENCES
A previously undescribed coronavirus associated with respiratory disease in humans.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 2004
- 513
- PDF
Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
- Biology, Medicine
- The New England journal of medicine
- 2003
- 3,180
- PDF
Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome
- Biology, Medicine
- Science
- 2003
- 2,060
- PDF
Characterization and Complete Genome Sequence of a Novel Coronavirus, Coronavirus HKU1, from Patients with Pneumonia
- Biology, Medicine
- Journal of Virology
- 2005
- 1,069
- PDF
A Pancoronavirus RT-PCR Assay for Detection of All Known Coronaviruses
- Biology, Medicine
- Methods in molecular biology
- 2008
- 60
- PDF
Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study
- Medicine
- The Lancet
- 2003
- 1,747
- PDF
Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1967
- 342
- PDF