Isolation of a novel basic FGF-binding peptide with potent antiangiogenetic activity

Abstract

Basic fibroblast growth factor (bFGF), which plays an important role in tumour angiogenesis and progression, provides a potential target for cancer therapy. Here we screened a phage display heptapeptide library with bFGF and identified 11 specific bFGF-binding phage clones. Two of these clones had identical sequence and the corresponding peptide (referred… (More)
DOI: 10.1111/j.1582-4934.2008.00506.x

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