Isolation of a new phenazine antibiotic, DOB-41, from Pseudomonas species.

Abstract

A new phenazine antibiotic, DOB-41, was isolated from the culture broth of a Pseudomonas strain. The antibiotic obtained as yellow crystals showed UV maxima at 255 nm and 370 nm. A molecular formula, C19H18N2O6, was indicated by elemental analysis and mass spectrometry. The structure was elucidated by X-ray diffraction analysis. The antibiotic exhibited inhibitory activity against Gram-positive bacteria, and antitumor effect against leukemia P388 in mice.

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Cite this paper

@article{Shoji1988IsolationOA, title={Isolation of a new phenazine antibiotic, DOB-41, from Pseudomonas species.}, author={Junichi Shoji and Riichi Sakazaki and Hideo Nakai and Yoshihiro Terui and Takaaki Hattori and O Shiratori and Eisei Kondo and Tsuyoshi Konishi}, journal={The Journal of antibiotics}, year={1988}, volume={41 5}, pages={589-94} }