Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine.

@article{Filmus1988IsolationOA,
  title={Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine.},
  author={Jorge Filmus and Jon G. Church and Ronald N. Buick},
  journal={Molecular and cellular biology},
  year={1988},
  volume={8 10},
  pages={4243-9}
}
We report the isolation of a cDNA clone corresponding to a transcript that is accumulated differentially in rat intestine during development. Clone OCI-5 was selected from the rat intestinal cell line IEC-18, which represents primitive intestinal epithelial crypt cells. Expression was high in rat fetal intestine between 15 and 19 days of development and thereafter was progressively down regulated, becoming undetectable after weaning. Clone OCI-5 detected homologous sequences in human and murine… CONTINUE READING

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