• DOI:10.1126/SCIENCE.6189183
Corpus ID: 390173

Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).

@article{BarreSinoussi1983IsolationOA,
  title={Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).},
  author={F. Barré-Sinoussi and J. Chermann and F. Rey and M. Nugeyre and S. Chamaret and J. Gruest and C. Dauguet and C. Axler-Blin and F. V{\'e}zinet-Brun and C. Rouzioux and W. Rozenbaum and L. Montagnier},
  journal={Science},
  year={1983},
  volume={220 4599},
  pages={
          868-71
        }
}

F. Barré-Sinoussi, J. Chermann, +9 authors L. Montagnier

Published 1983

Biology, Medicine

Science

A retrovirus belonging to the family of recently discovered human T-cell leukemia viruses (HTLV), but clearly distinct from each previous isolate, has been isolated from a Caucasian patient with signs and symptoms that often precede the acquired immune deficiency syndrome (AIDS). This virus is a typical type-C RNA tumor virus, buds from the cell membrane, prefers magnesium for reverse transcriptase activity, and has an internal antigen (p25) similar to HTLV p24. Antibodies from serum of this… CONTINUE READING

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