Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).

@article{BarreSinoussi1983IsolationOA,
  title={Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS).},
  author={Françoise Barré-Sinoussi and Jean Claude Chermann and Françoise Rey and M. T. Nugeyre and Solange Chamaret and Jacqueline Gruest and Charles Dauguet and C Axler-Blin and F V{\'e}zinet-Brun and Christine Rouzioux and Willy Rozenbaum and Luc Montagnier},
  journal={Science},
  year={1983},
  volume={220 4599},
  pages={
          868-71
        }
}
A retrovirus belonging to the family of recently discovered human T-cell leukemia viruses (HTLV), but clearly distinct from each previous isolate, has been isolated from a Caucasian patient with signs and symptoms that often precede the acquired immune deficiency syndrome (AIDS). This virus is a typical type-C RNA tumor virus, buds from the cell membrane, prefers magnesium for reverse transcriptase activity, and has an internal antigen (p25) similar to HTLV p24. Antibodies from serum of this… Expand
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