Isolation of a Membrane Protein Complex for Type VII Secretion in Staphylococcus aureus.

@article{Aly2017IsolationOA,
  title={Isolation of a Membrane Protein Complex for Type VII Secretion in Staphylococcus aureus.},
  author={Khaled A Aly and Mark T. Anderson and Ryan Jay Ohr and Dominique Missiakas},
  journal={Journal of bacteriology},
  year={2017},
  volume={199 23}
}
The ESAT6-like secretion system (ESS) of Staphylococcus aureus promotes effector protein transport across the bacterial envelope. Genes in the ESS cluster are required for S. aureus establishment of persistent abscess lesions and the modulation of immune responses during bloodstream infections. However, the biochemical functions of most of the ESS gene products, specifically the identity of secretion machine components, are unknown. Earlier work demonstrated that deletion of essB, which encodes… CONTINUE READING
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