Isolation of a Hypomorphic skn-1 Allele That Does Not Require a Balancer for Maintenance

Abstract

In Caenorhabditis elegans, the transcription factor SKN-1 has emerged as a central coordinator of stress responses and longevity, increasing the need for genetic tools to study its regulation and function. However, current loss-of-function alleles cause fully penetrant maternal effect embryonic lethality, and must be maintained with genetic balancers that… (More)
DOI: 10.1534/g3.115.023010

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