Isolation of Intranuclear Inclusion Producing Agents from Infants with Illnesses Resembling Cytomegalic Inclusion Disease.∗ †

@article{Weller1957IsolationOI,
  title={Isolation of Intranuclear Inclusion Producing Agents from Infants with Illnesses Resembling Cytomegalic Inclusion Disease.∗ †},
  author={Thomas H. Weller and Juliete Macauley and John M. Craig and P M Wirth},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  year={1957},
  volume={94},
  pages={12 - 4}
}
Summary Viruses that produce similar cytopathic changes in vitro characterized by presence of intranuclear inclusions have been isolated from 3 infants during life. The first derived from a liver biopsy from a 3-months-old child (Davis) with microcephaly, persistent jaundice, and hepatosplenomegaly; cytomegalic cells were demonstrated in the liver specimen. From a second child, virus was isolated from a liver biopsy, and on three occasions between the 14th and 91st day of life from the urine… 

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