Isolation of Dlx and Emx gene cognates in an agnathan species, Lampetra japonica, and their expression patterns during embryonic and larval development: conserved and diversified regulatory patterns of homeobox genes in vertebrate head evolution.

@article{Myojin2001IsolationOD,
  title={Isolation of Dlx and Emx gene cognates in an agnathan species, Lampetra japonica, and their expression patterns during embryonic and larval development: conserved and diversified regulatory patterns of homeobox genes in vertebrate head evolution.},
  author={Miyoko Myojin and Tatsuya Ueki and Fumiaki Sugahara and Yasunori Murakami and Yasuyo Shigetani and Shinichi Aizawa and Shigeki Hirano and Shigeru Kuratani},
  journal={The Journal of experimental zoology},
  year={2001},
  volume={291 1},
  pages={68-84}
}
Agnathan cognates of vertebrate homeobox genes, Emx and Dlx, were isolated from embryonic cDNA of a Japanese marine lamprey, Lampetra japonica. Analyses of amino acid sequences indicated that the Dlx cognate was closely related to the common ancestor of gnathostome Dlx1 and Dlx6 groups and termed LjDlx1/6. Southern blot analyses could not rule out the possibility that L. japonica possesses more than one paralog for both LjDlx1/6 and LjEmx, the lamprey cognate of Emx. Expression of LjDlx1/6 was… CONTINUE READING

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The expression pattern of LjEmx changed dramatically during embryogenesis ; expression was seen initially in the entire neural tube and mesoderm , which were secondarily downregulated , and secondarily in cranial nerve ganglia and in the craniofacial mesenchyme .
The expression pattern of LjEmx changed dramatically during embryogenesis ; expression was seen initially in the entire neural tube and mesoderm , which were secondarily downregulated , and secondarily in cranial nerve ganglia and in the craniofacial mesenchyme .
The expression pattern of LjEmx changed dramatically during embryogenesis ; expression was seen initially in the entire neural tube and mesoderm , which were secondarily downregulated , and secondarily in cranial nerve ganglia and in the craniofacial mesenchyme .
The expression pattern of LjEmx changed dramatically during embryogenesis ; expression was seen initially in the entire neural tube and mesoderm , which were secondarily downregulated , and secondarily in cranial nerve ganglia and in the craniofacial mesenchyme .
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