Correlation of presence of Candida and epithelial dysplasia in oral mucosal lesions.
Background: Candida is the most common fungal pathogen in the human oral cavity. So they have the ability to cause opportunistic infection called as oral candidiasis. This study was designed to isolate Candida by using Sabouraud’s Dextrose agar media and its association with Oral mucosal lesions. Methods: 45 patients of clinically diagnosed oral mucosal lesions, 5 each was of Leukoplakia, Lichen Planus, Lichenoid Reaction, Chewer’s Mucosa, Squamous cell Carcinoma, Angular Cheilitis, Denture Stomatitis, Aphthous ulcers were selected. Samples were collected from oral mucosal lesions for the candidal growth.The data obtained was statistically analyzed by using Chi Square test using SPSS version 16. Results: Out of 45 patients, 14 showed positive Candidal growth in which 5 Cases were of Leukoplakia, 3 of Lichen Planus, 2 each of Fibroma, Squamous cell carcinoma, Denture stomatitis. Conclusion: 14 Patients with Oral Mucosal Lesions showed positive fungal growth, so these patients are more susceptible for developing Oral Candidiasis as compared to the lesions with no Candidal growth.