Isolation of α-glucosidase inhibitors including a new flavonol glycoside from Dendrobium devonianum.

@article{Sun2014IsolationO,
  title={Isolation of α-glucosidase inhibitors including a new flavonol glycoside from Dendrobium devonianum.},
  author={Jing Sun and Fudong Zhang and Miao Yang and Junjie Zhang and Lijun Chen and Rui Zhan and Gangyi Yang and Yegao Chen},
  journal={Natural product research},
  year={2014},
  volume={28 21},
  pages={1900-5}
}
From the whole plant of Dendrobium devonianum, a new flavonol glycoside, 5-hydroxy-3-methoxy-flavone-7-O-[β-D-apiosyl-(1 → 6)]-β-D-glucoside, as well as 13 known compounds, was isolated. Their structures were identified based on extensive spectroscopic studies including HR-EI-MS, (1)H, (13)C NMR, DEPT, H-H COSY, HSQC, HMBC and NOESY spectra. The new compound and gigantol were evaluated for their α-glucosidase inhibitory activity, and both displayed more potent α-glucosidase inhibitory activity… CONTINUE READING

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