The bactericidal action of the antibiotic streptonigrin is enhanced by large intracellular iron pools. Using this observation, we have utilized a simple enrichment protocol to aid in the isolation of iron uptake mutants of N. meningitidis, based on the relative resistance of iron-starved meningococci to streptonigrin. One such mutant, FAM29, was impaired in… (More)
Figures and Tables
Sorry, we couldn't extract any figures or tables for this paper.