Isolation and synthesis of antiproliferative eupolauridine alkaloids of Ambavia gerrardii from the Madagascar Dry Forest.

Abstract

Investigation of the Madagascan endemic plant Ambavia gerrardii for antiproliferative activity against the A2780 ovarian cancer cell line led to the isolation of the three new alkaloids 8-hydroxyeupolauridine (1), 9-methoxyeupolauridine 1-oxide (2), and 11-methoxysampangine (3) and the three known alkaloids 4-6. The structures of 1 and 2 were confirmed by… (More)
DOI: 10.1021/np200093n

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Cite this paper

@article{Pan2011IsolationAS, title={Isolation and synthesis of antiproliferative eupolauridine alkaloids of Ambavia gerrardii from the Madagascar Dry Forest.}, author={Ende Pan and Shugeng Cao and Peggy J. Brodie and Martin W. Callmander and Richard Randrianaivo and Stephan R Rakotonandrasana and Etienne A Rakotobe and Vincent Emile Rasamison and Karen Tendyke and Yongchun Shen and Edward Suh and David G I Kingston}, journal={Journal of natural products}, year={2011}, volume={74 5}, pages={1169-74} }