Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta migratoria.

@article{Hetru1991IsolationAS,
  title={Isolation and structural characterization of an insulin-related molecule, a predominant neuropeptide from Locusta migratoria.},
  author={Charles Hetru and Ka Wan Li and Philippe Bulet and Marie Lagueux and Jules A. Hoffmann},
  journal={European journal of biochemistry},
  year={1991},
  volume={201 2},
  pages={495-9}
}
Neurohaemal lobes of corpora cardiaca of Locusta migratoria are an established storage site for neurohormones produced by the neurosecretory cells of the brain. As previously reported [Hietter, H., Van Dorsselaer, A., Green, B., Denoroy, L., Hoffmann, J.A. & Luu, B. (1990) Eur. J. Biochem. 187, 241-247], the isolation and characterization of a novel 5-kDa peptide from these lobes served as the basis for oligonucleotide screening of cDNA libraries prepared from poly(A) RNA from neurosecretory… CONTINUE READING
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