Isolation and purification of superbins I and II from Austrelaps superbus (copperhead) snake venom and their anticoagulant and antiplatelet effects.

@article{Subburaju1997IsolationAP,
  title={Isolation and purification of superbins I and II from Austrelaps superbus (copperhead) snake venom and their anticoagulant and antiplatelet effects.},
  author={S. Subburaju and R. Kini},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={1997},
  volume={35 8},
  pages={
          1239-50
        }
}
  • S. Subburaju, R. Kini
  • Published 1997
  • Chemistry, Medicine
  • Toxicon : official journal of the International Society on Toxinology
Two proteins with anticoagulant and antiplatelet activities were purified from Austrelaps superbus (copperhead) venom by gel filtration, ion-exchange and reverse-phase chromatographic methods. These purified proteins were designated superbins I and II. Superbin I was homogeneous, as indicated by electrospray ionization-mass spectrometry, with a mol. wt of 13,252.3 +/- 1.6, whereas superbin II contained two closely related proteins of mol. wts 13,235.5 +/- 1.1 and 13,212.9 +/- 1.2. Both… Expand
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