Isolation and purification of a modified phenazine, griseoluteic acid, produced by Streptomyces griseoluteus P510.

@article{Wang2011IsolationAP,
  title={Isolation and purification of a modified phenazine, griseoluteic acid, produced by Streptomyces griseoluteus P510.},
  author={Ying Wang and Qin Luo and Xuehong Zhang and Wei Wang},
  journal={Research in microbiology},
  year={2011},
  volume={162 3},
  pages={
          311-9
        }
}
Antibiotic phenazine derivatives and their formation pathways were studied in a new Streptomyces strain P510. Culture characteristics and 16S rRNA nucleotide analysis confirmed strain P510 as Streptomyces griseoluteus. The culture medium of this strain showed strong antimicrobial and antifungal activities. Using organic solvent extraction, silica gel column chromatography and HPLC, a modified phenazine, griseoluteic acid, and a shikimic acid-derived metabolite, p-hydroxybenzaldehyde, were… CONTINUE READING
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