Isolation and partial characterization of proteins from platelet pseudopods.

Abstract

Isolated pseudopods of human platelets activated by ADP, thrombin, or low temperature contain, as a major constituent, a 70,000-dalton membrane protein. This protein, which is labeled in intact platelets by [125I]iodonaphthylazide, is either pushed out of the membrane plane during activation or undergoes a conformational change or, as a result of activation… (More)

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