Isolation and identification of two isomeric trihydroxy octadecenoic acids with prostaglandin E-like activity from onion bulbs (Allium cepa).

@article{Ustnes1985IsolationAI,
  title={Isolation and identification of two isomeric trihydroxy octadecenoic acids with prostaglandin E-like activity from onion bulbs (Allium cepa).},
  author={L Ust{\"u}nes and Magda Claeys and G Laekeman and Arnold G. Herman and Arnold J. Vlietinck and Andr{\'e} Ozer},
  journal={Prostaglandins},
  year={1985},
  volume={29 5},
  pages={
          847-65
        }
}
Two fractions with prostaglandin E-like activity were isolated from onion (Allium cepa) by using XAD-2 adsorption, silicic acid column chromatography and thin layer chromatography. The fractions were analyzed by gas chromatography/mass spectrometry and were characterized as isomeric mixtures of 9,10,13-trihydroxy-11-octadecenoic and 9,12,13-trihydroxy-10-octadecenoic acid, which are lipoxygenase metabolites of linoleic acid. Bio-assay, for which cascade superfusion was used and the rabbit… CONTINUE READING

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