Isolation and identification of the major metabolite of albuterol in human urine.

Abstract

The major urinary metabolite of albuterol in man was isolated and purified by ion-exchange chromatography and countercurrent distribution. On the basis of proton magnetic resonance, infrared, and mass-spectral analysis, enzymic hydrolysis, and assay of inorganic sulfate after acid hydrolysis, the metabolite has been identified as the 4'-O-sulfate ester of… (More)

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@article{Lin1977IsolationAI, title={Isolation and identification of the major metabolite of albuterol in human urine.}, author={C S Lin and Y Li and J H McGlotten and J. Bruce Morton and Samson Symchowicz}, journal={Drug metabolism and disposition: the biological fate of chemicals}, year={1977}, volume={5 3}, pages={234-8} }